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Dermochronology
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Solar scars guardian
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Redefining dermis
Timlog™
Just as the skin, trees have memory, their life story can be read in their rings. Tree rings record not only age (dendrochronology), but also each season & climate experience (wet, hot, early frosts, sunlight, etc). Just as trees need sunlight, skin does too, but an excess of it can lead to premature aging which alters skin’s dermochronology
A photoaged skin (scar-like dermis) is characterized by a high content of MMPs which degrade the extracellular matrix and alter collagen density & organization (synthesis & deposition). The guardians against MMPs are TIMPs, which are specific inhibitors that bind to them
Timlog™ is a plant-based human TIMP-2 (Tissue inhibitor of metalloproteinases) produced in Wild plants as biofactories technology. TIMP-2 is an inhibitor of all MMPs (specifically of MMP-2). Additionally, it increases fibromodulin which has an important role in organizing the ECM by binding to collagen, resulting in delay of fibril formation and the formation of thinner fibers
Timlog™ acts as a guardian for skin’s dermochronology, repairing dermal solar scars redefining the past
Before & After
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Non UV-exposed |
UV-exposed + Timlog™ | UV-exposed |
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T0 days![]() |
T28 days![]() |
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+6.9% isotropy |
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T0 days
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T28 days
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+37% fibers density |
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