N. benthamiana is a historical plant-based model system for the transient expression of high purity proteins in a non-GM system. As opposed to recombinant production by Gram(-) bacteria which may contain endotoxins, synthesis of proteins in plants allows to obtain safe plant-based biotechnological ingredients with proper modifications and high activity.
Metabolism, pollution, or UV light induce ROS and RNS, as well as inflammation, affecting the skin. The thioredoxin system is a major antioxidant system containing Thioredoxin-1 (TRX-1) which acts as a thiol/disulfide redox controller, scavenging ROS for photoaging protection and reducing human tyrosinase for a decrease of melanin synthesis.
Pureoxin™ contains plant-Thioredoxin-1 (plant-TRX-1), a multifunctional protein able to protect the skin from inflammaging and photoaging caused by ROS, MMP-9 and TNFα induced by radiation. Moreover, it can decrease the content of superficial melanin helping to lighten and illuminate skin tone.
Before & After
Up to 74% reduction of superficial melanin after 56 days
–3.8-fold UV damage vs placebo in 28 days